Prothionamide

Chemical compound
  • J04AD01 (WHO)
Identifiers
  • 2-propylpyridine-4-carbothioamide
CAS Number
  • 14222-60-7 checkY
PubChem CID
  • 666418
ChemSpider
  • 579891 ☒N
UNII
  • 76YOO33643
CompTox Dashboard (EPA)
  • DTXSID7045940 Edit this at Wikidata
ECHA InfoCard100.034.615 Edit this at WikidataChemical and physical dataFormulaC9H12N2SMolar mass180.27 g·mol−13D model (JSmol)
  • Interactive image
  • CCCc1cc(ccn1)C(=S)N
InChI
  • InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) ☒N
  • Key:VRDIULHPQTYCLN-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis and leprosy.[1][2]

References

  1. ^ Wang F, Langley R, Gulten G, et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". J. Exp. Med. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
  2. ^ Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". Am. J. Trop. Med. Hyg. 74 (3): 457–61. doi:10.4269/ajtmh.2006.74.457. PMID 16525107. S2CID 21415032.
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Antimycobacterials, including tuberculosis treatment and leprostatic agents (J04)
Nucleic acid inhibitor
Rifamycins/
RNA polymerase inhibitor
Antifolates/DSI
ASA
Topoisomerase inhibitors/
quinolones
Protein synthesis inhibitor
Aminoglycosides
Oxazolidone
Polypeptide antibiotics
Cell envelope antibiotic
Peptidoglycan layer
Arabinogalactan layer
Mycolic acid layer
Other/unknownCombinations
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