Prothionamide
Chemical compound
- J04AD01 (WHO)
- 2-propylpyridine-4-carbothioamide
- 14222-60-7 Y
- 666418
- 579891 N
- 76YOO33643
- DTXSID7045940
- Interactive image
- CCCc1cc(ccn1)C(=S)N
InChI
- InChI=1S/C9H12N2S/c1-2-3-8-6-7(9(10)12)4-5-11-8/h4-6H,2-3H2,1H3,(H2,10,12) N
- Key:VRDIULHPQTYCLN-UHFFFAOYSA-N N
Protionamide (or prothionamide) is a drug used in the treatment of tuberculosis and leprosy.[1][2]
References
- ^ Wang F, Langley R, Gulten G, et al. (January 2007). "Mechanism of thioamide drug action against tuberculosis and leprosy". J. Exp. Med. 204 (1): 73–8. doi:10.1084/jem.20062100. PMC 2118422. PMID 17227913.
- ^ Fajardo TT, Guinto RS, Cellona RV, Abalos RM, Dela Cruz EC, Gelber RH (March 2006). "A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy". Am. J. Trop. Med. Hyg. 74 (3): 457–61. doi:10.4269/ajtmh.2006.74.457. PMID 16525107. S2CID 21415032.
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Antimycobacterials, including tuberculosis treatment and leprostatic agents (J04)
Rifamycins/ RNA polymerase inhibitor | |
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Antifolates/DSI | |
ASA | |
Topoisomerase inhibitors/ quinolones |
Aminoglycosides | |
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Oxazolidone | |
Polypeptide antibiotics |
Peptidoglycan layer |
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Arabinogalactan layer |
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Mycolic acid layer |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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