NLRP13

Protein-coding gene in the species Homo sapiens
NLRP13
Identifiers
AliasesNLRP13, CLR19.7, NALP13, NOD14, PAN13, NLR family, pyrin domain containing 13, NLR family pyrin domain containing 13
External IDsOMIM: 609660 HomoloGene: 65313 GeneCards: NLRP13
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for NLRP13
Genomic location for NLRP13
Band19q13.43Start55,891,699 bp[1]
End55,932,336 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • oocyte

  • secondary oocyte

  • bone marrow cells

  • thymus

  • skeletal muscle tissue

  • urinary bladder

  • liver

  • breast

  • cervix

  • male reproductive gland
    n/a
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

126204

n/a

Ensembl

ENSG00000173572

n/a

UniProt

Q86W25

n/a

RefSeq (mRNA)

NM_176810
NM_001321057

n/a

RefSeq (protein)

NP_001307986
NP_789780

n/a

Location (UCSC)Chr 19: 55.89 – 55.93 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

NLRP13, short for NOD-like receptor family pyrin domain containing 13, is an intracellular protein of mammals. It is also known as NALP13, NOD14, PAN13, and CLR19.7, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.[3] The function of NLRP13 is currently unknown.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173572 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Tschopp J, Martinon F, Burns K (February 2003). "NALPs: a novel protein family involved in inflammation". Nat. Rev. Mol. Cell Biol. 4 (2): 95–104. doi:10.1038/nrm1019. PMID 12563287. S2CID 31417018.

Further reading

  • Enjuanes A, Benavente Y, Bosch F, et al. (2008). "Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia". Cancer Res. 68 (24): 10178–86. doi:10.1158/0008-5472.CAN-08-2221. PMID 19074885.
  • Inohara N, Nuñez G (2003). "NODs: intracellular proteins involved in inflammation and apoptosis". Nat. Rev. Immunol. 3 (5): 371–82. doi:10.1038/nri1086. PMID 12766759. S2CID 8088987.
  • v
  • t
  • e
CARD domain containing
Pyrin domain containingApoptosis inhibitory protein
  • NAIP
Family member X1


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