Feprazone

NSAID analgesic drug
  • M02AA16 (WHO)
Identifiers
  • 4-(3-methylbut-2-enyl)-1,2-di(phenyl)pyrazolidine-3,5-dione
CAS Number
  • 30748-29-9 checkY
PubChem CID
  • 35455
ChemSpider
  • 32612 checkY
UNII
  • 7BVX6J0CGR
KEGG
  • D01305 checkY
CompTox Dashboard (EPA)
  • DTXSID3023051 Edit this at Wikidata
ECHA InfoCard100.045.735 Edit this at WikidataChemical and physical dataFormulaC20H20N2O2Molar mass320.392 g·mol−13D model (JSmol)
  • Interactive image
  • O=C2N(c1ccccc1)N(C(=O)C2C\C=C(/C)C)c3ccccc3
InChI
  • InChI=1S/C20H20N2O2/c1-15(2)13-14-18-19(23)21(16-9-5-3-6-10-16)22(20(18)24)17-11-7-4-8-12-17/h3-13,18H,14H2,1-2H3 checkY
  • Key:RBBWCVQDXDFISW-UHFFFAOYSA-N checkY
  (verify)

Feprazone (or prenazone) is a drug used for joint and muscular pain.[1]

It is an analog of phenylbutazone but instead of a n-butyl group it is prenylated.

References

  1. ^ Koyama T, Izawa Y, Wada H, Makita T, Hashimoto Y, Enomoto M (June 1982). "Toxicological aspects of feprazone, a new nonsteroidal anti-inflammatory drug". Toxicology and Applied Pharmacology. 64 (2): 255–70. doi:10.1016/0041-008X(82)90222-8. PMID 7123554.
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Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones /
pyrazolidinessalicylatesacetic acid derivatives
and related substancesoxicamspropionic acid
derivatives (profens)n-arylanthranilic
acids (fenamates)COX-2 inhibitors
(coxibs)otherNSAID
combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
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