Ampyrone
Names | |
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Preferred IUPAC name 4-Amino-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one[1] | |
Other names solvapyrin A, aminoazophene, aminoantipyrene, aminoantipyrine, metapyrazone | |
Identifiers | |
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ECHA InfoCard | 100.001.321 |
PubChem CID |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C11H13N3O1[2] |
Molar mass | 203.24 g/mol |
Density | 1.207g/cm3 |
Melting point | 106 to 110 °C (223 to 230 °F; 379 to 383 K) |
Boiling point | 309 °C (588 °F; 582 K) @760mmHg |
Hazards | |
Flash point | 140.7 °C (285.3 °F; 413.8 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references |
Chemical compound
Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties.[2] Its use as a drug is discouraged due to the risk of agranulocytosis.[3] It is used as a reagent for biochemical reactions producing peroxides or phenols.[2] Ampyrone stimulates liver microsomes and is also used to measure extracellular water.[2]
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Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
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