Tiamulin
Chemical compound
- QJ01XQ01 (WHO)
- Veterinary use only
- (4R,5S,6S,8R,9aR,10R)-5-Hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate
- 55297-95-5 Y
- 656958
- 571196 N
- E38WZ4U54R
- CHEBI:44137 N
- ChEMBL498466 N
- DTXSID2046701
- Interactive image
- CCN(CC)CCSCC(=O)O[C@@H]1C[C@@]([C@H]([C@@H]([C@@]23CC[C@H]([C@@]1([C@@H]2C(=O)CC3)C)C)C)O)(C)C=C
InChI
- InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1 N
- Key:UURAUHCOJAIIRQ-QGLSALSOSA-N N
Tiamulin (previously thiamutilin) is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.[1][2]
Tiamulin is a diterpene antimicrobial with a pleuromutilin chemical structure similar to that of valnemulin.[3]
References
- ^ "Tiamulin in Veterinary Medicine". HACCP. Archived from the original on 2009-06-10.
- ^ Long KS, Hansen LH, Jakobsen L, Vester B (April 2006). "Interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center". Antimicrobial Agents and Chemotherapy. 50 (4): 1458–62. doi:10.1128/AAC.50.4.1458-1462.2006. PMC 1426994. PMID 16569865.
- ^ "Tiamulin Summary Report" (PDF). EMEA.
- v
- t
- e
Aminoglycosides (initiation inhibitors) |
| ||||||
---|---|---|---|---|---|---|---|
Tetracycline antibiotics (tRNA binding) |
|
Steroid antibacterials |
---|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This systemic antibiotic-related article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e