SSBP4

Protein-coding gene in the species Homo sapiens
SSBP4
Identifiers
AliasesSSBP4, single stranded DNA binding protein 4
External IDsOMIM: 607391; MGI: 1924150; HomoloGene: 41881; GeneCards: SSBP4; OMA:SSBP4 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for SSBP4
Genomic location for SSBP4
Band19p13.11Start18,418,864 bp[1]
End18,434,562 bp[1]
Gene location (Mouse)
Chromosome 8 (mouse)
Chr.Chromosome 8 (mouse)[2]
Chromosome 8 (mouse)
Genomic location for SSBP4
Genomic location for SSBP4
Band8|8 B3.3Start70,597,490 bp[2]
End70,608,872 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • anterior pituitary

  • canal of the cervix

  • left uterine tube

  • caudate nucleus

  • nucleus accumbens

  • putamen

  • Brodmann area 9

  • amygdala

  • right coronary artery
Top expressed in
  • superior frontal gyrus

  • entorhinal cortex

  • olfactory tubercle

  • ankle joint

  • subiculum

  • cerebellar cortex

  • nucleus accumbens

  • lip

  • ventromedial nucleus

  • dorsomedial hypothalamic nucleus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • single-stranded DNA binding
  • DNA binding
  • RNA polymerase II cis-regulatory region sequence-specific DNA binding
  • DNA-binding transcription activator activity, RNA polymerase II-specific
  • protein binding
Cellular component
  • nucleus
Biological process
  • transcription by RNA polymerase II
  • positive regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

170463

76900

Ensembl

ENSG00000130511

ENSMUSG00000070003

UniProt

Q9BWG4

n/a

RefSeq (mRNA)

NM_001009998
NM_032627

NM_133772

RefSeq (protein)

NP_001009998
NP_116016

n/a

Location (UCSC)Chr 19: 18.42 – 18.43 MbChr 8: 70.6 – 70.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Single-stranded DNA-binding protein 4 is a protein that in humans is encoded by the SSBP4 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130511 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070003 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Castro P, Liang H, Liang JC, Nagarajan L (July 2002). "A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity". Genomics. 80 (1): 78–85. doi:10.1006/geno.2002.6805. PMID 12079286.
  6. ^ "SSBP4 - Single-stranded DNA-binding protein 4 - Homo sapiens (Human) - SSBP4 gene & protein". www.uniprot.org. Retrieved 2019-01-23.

Further reading

  • Guo X, et al. (May 2018). "A Comprehensive cis-eQTL Analysis Revealed Target Genes in Breast Cancer Susceptibility Loci Identified in Genome-wide Association Studies". American Journal of Human Genetics. 102 (5): 890–903. doi:10.1016/j.ajhg.2018.03.016. PMC 5986971. PMID 29727689.
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Initiation
Prokaryotic
(initiation)
Eukaryotic
(preparation in
G1 phase)
Both
Replication
Prokaryotic
(elongation)
Eukaryotic
(synthesis in
S phase)
Both
Termination
Stub icon

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