Endralazine

Chemical compound
  • C02DB03 (WHO)
Identifiers
  • 6-benzoyl-3-hydrazinyl-5H,6H,7H,8H-pyrido[4,3-c]pyridazine
CAS Number
  • 39715-02-1 checkY
PubChem CID
  • 47608
ChemSpider
  • 43316 ☒N
UNII
  • L44741F05P
KEGG
  • D08254 checkY
ChEMBL
  • ChEMBL254193 ☒N
CompTox Dashboard (EPA)
  • DTXSID40192791 Edit this at Wikidata
Chemical and physical dataFormulaC14H15N5OMolar mass269.308 g·mol−13D model (JSmol)
  • Interactive image
  • c1ccc(cc1)C(=O)N2CCc3c(c/c(=N/N)/[nH]n3)C2
InChI
  • InChI=1S/C14H15N5O/c15-16-13-8-11-9-19(7-6-12(11)17-18-13)14(20)10-4-2-1-3-5-10/h1-5,8H,6-7,9,15H2,(H,16,18) ☒N
  • Key:ALAXZYHFVBSJKZ-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Endralazine is an antihypertensive of the hydrazinophthalazine chemical class.[1] It is not approved for use in the United States.

References

  1. ^ Meredith PA, Elliott HL, McSharry DR, Kelman AW, Reid JL (July 1983). "The pharmacokinetics of endralazine in essential hypertensives and in normotensive subjects". British Journal of Clinical Pharmacology. 16 (1): 27–32. doi:10.1111/j.1365-2125.1983.tb02139.x. PMC 1427948. PMID 6882620.
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Nonsympatholytic vasodilatory antihypertensives (C02)
Nitrovasodilator (arterioles and venules)Hydrazinophthalazines (arterioles)Potassium channel openers (arterioles)Calcium channel blockers (arterioles)
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