Cloprednol
Chemical compound
- H02AB14 (WHO)
- (9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
- 5251-34-3
- 10023463
- 4447592
- SYP56O3GJG
- D03561
- ChEMBL1697832
- DTXSID1022849
- Interactive image
- O=C\1\C=C/[C@]4(C(=C/1)C(\Cl)=C/[C@@H]2[C@@H]4[C@@H](O)C[C@@]3([C@@](O)(C(=O)CO)CC[C@@H]23)C)C
Cloprednol is a synthetic glucocorticoid.[1] It has been investigated for use in asthma.[2]
References
- ^ Ortega E, Rodriguez C, Strand LJ, Bessler S, Segre E (1976). "Metabolic effects of cloprednol-a new systemic corticosteroid". J Clin Pharmacol. 16 (2–3): 122–8. doi:10.1002/j.1552-4604.1976.tb02393.x. PMID 1254734. S2CID 38774591.[permanent dead link]
- ^ Ellis EF, Morris HG, Kiechel F, Pollock JD, Strand LJ (October 1979). "Short-term efficacy and side effects of cloprednol in children with asthma". J Clin Pharmacol. 19 (10): 675–83. doi:10.1002/j.1552-4604.1979.tb01631.x. PMID 512064. S2CID 38757781.[permanent dead link]
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Mineralocorticoids and antimineralocorticoids (H02)
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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