EDN1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/7/75/PDB_1edn_EBI.jpg/250px-PDB_1edn_EBI.jpg) |
Cấu trúc được biết đến |
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PDB | Tìm trên Human UniProt: PDBe RCSB |
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Danh sách mã id PDB |
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1EDN, 1EDP, 1T7H, 1V6R, 6DK5, 5GLH |
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Mã định danh |
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Danh pháp | EDN1, ARCND3, ET1, HDLCQ7, QME, endothelin 1, PPET1 |
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ID ngoài | HomoloGene: 1476 GeneCards: EDN1 |
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Vị trí gen (Người) |
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![Nhiễm sắc thể 6 (người)](//upload.wikimedia.org/wikipedia/commons/thumb/0/03/Ideogram_human_chromosome_6.svg/300px-Ideogram_human_chromosome_6.svg.png) | NST | Nhiễm sắc thể 6 (người)[1] |
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| Băng | 6p24.1 | Bắt đầu | 12,290,361 bp[1] |
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Kết thúc | 12,297,194 bp[1] |
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Bản thể gen |
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Chức năng phân tử | • hormone activity • signaling receptor binding • cytokine activity • endothelin B receptor binding • GO:0001948, GO:0016582 protein binding • endothelin A receptor binding
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Thành phần tế bào | • tế bào chất • Weibel-Palade body • basal part of cell • extracellular region • rough endoplasmic reticulum lumen • extracellular space • transport vesicle
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Quá trình sinh học | • skeletal system development • response to amino acid • positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway • positive regulation of MAP kinase activity • regulation of sensory perception of pain • Co mạch máu • body fluid secretion • positive regulation of sarcomere organization • positive regulation of cardiac muscle hypertrophy • cell surface receptor signaling pathway • multicellular organism aging • artery smooth muscle contraction • cellular response to interferon-gamma • positive regulation of chemokine-mediated signaling pathway • phosphatidylinositol 3-kinase signaling • response to leptin • positive regulation of mitotic nuclear division • cellular response to hypoxia • response to muscle stretch • cellular response to calcium ion • cellular response to transforming growth factor beta stimulus • positive regulation of renal sodium excretion • blood vessel morphogenesis • negative regulation of blood coagulation • response to nicotine • in utero embryonic development • neutrophil chemotaxis • heart development • positive regulation of prostaglandin secretion • vein smooth muscle contraction • cartilage development • rhythmic excitation • protein kinase C-activating G protein-coupled receptor signaling pathway • cellular response to glucocorticoid stimulus • branching involved in blood vessel morphogenesis • negative regulation of hormone secretion • positive regulation of smooth muscle contraction • negative regulation of nitric-oxide synthase biosynthetic process • positive regulation of prostaglandin-endoperoxide synthase activity • positive regulation of urine volume • positive regulation of JUN kinase activity • leukocyte activation • membrane depolarization • GO:1901227 negative regulation of transcription by RNA polymerase II • response to ozone • respiratory gaseous exchange by respiratory system • positive regulation of heart rate • regulation of blood pressure • response to lipopolysaccharide • response to prostaglandin F • regulation of vasoconstriction • cellular response to interleukin-1 • response to salt • positive regulation of cell size • middle ear morphogenesis • sensory perception of pain • prostaglandin biosynthetic process • dorsal/ventral pattern formation • phospholipase D-activating G protein-coupled receptor signaling pathway • positive regulation of odontogenesis • regulation of pH • positive regulation of smooth muscle cell proliferation • protein kinase C deactivation • histamine secretion • maternal process involved in parturition • GO:0007243 intracellular signal transduction • response to hypoxia • neural crest cell development • regulation of systemic arterial blood pressure by endothelin • nitric oxide transport • positive regulation of cell migration • response to testosterone • positive regulation of cytosolic calcium ion concentration • epithelial fluid transport • positive regulation of nitric oxide biosynthetic process • cell-cell signaling • cellular response to tumor necrosis factor • response to activity • response to dexamethasone • superoxide anion generation • positive regulation of endothelial cell migration • cellular response to peptide hormone stimulus • cellular response to fatty acid • peptide hormone secretion • cellular response to mineralocorticoid stimulus • positive regulation of cell population proliferation • inositol phosphate-mediated signaling • positive regulation of hormone secretion • negative regulation of smooth muscle cell apoptotic process • calcium-mediated signaling • response to transforming growth factor beta • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of DNA-binding transcription factor activity • positive regulation of cell growth involved in cardiac muscle cell development • positive regulation of neutrophil chemotaxis • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • regulation of glucose transmembrane transport • negative regulation of gene expression • positive regulation of NIK/NF-kappaB signaling • positive regulation of vascular associated smooth muscle cell proliferation
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Nguồn: Amigo / QuickGO |
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Gen cùng nguồn |
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Loài | Người | Chuột |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | |
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NP_001161791 NP_001946 NP_001161791 NP_001946 |
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Vị trí gen (UCSC) | Chr 6: 12.29 – 12.3 Mb | n/a |
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PubMed | [2] | n/a |
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Wikidata |
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