Izepamicin
 | |
| Klinički podaci | |
|---|---|
| Drugs.com | Monografija |
| Identifikatori | |
| ATC kod | J01GB11 (WHO) |
| PubChem | CID 456297 |
| UNII | G7K224460P  Y |
| ChEMBL | CHEMBL272080 Y |
| Sinonimi | (2S)-3-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylaminooxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxypropanamide |
| Hemijski podaci | |
| Formula | C22H43N5O12 |
| Molarna masa | 569,603 |
SMILES
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InChI
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Izepamicin je organsko jedinjenje, koje sadrži 22 atoma ugljenika i ima molekulsku masu od 569,603 Da.
Osobine
| Osobina | Vrednost |
|---|---|
| Broj akceptora vodonika | 16 |
| Broj donora vodonika | 12 |
| Broj rotacionih veza | 9 |
| Particioni koeficijent[1] (ALogP) | -7,3 |
| Rastvorljivost[2] (logS, log(mol/L)) | -0,4 |
| Polarna površina[3] (PSA, Å2) | 297,7 |
Reference
- ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
- ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
- ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura
- Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
- Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.
Spoljašnje veze
- Isepamicin
- p
- r
- u
| Aminoglikozidi (Inhibitori inicijacija) |
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|---|---|---|---|---|---|
| Tetraciklinski antibiotici (tRNK vezivanje) |
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| Steroidni antibiotici |
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 | Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |
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