ZHX2 |
---|
![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e7/Protein_ZHX2_PDB_2dmp.png/250px-Protein_ZHX2_PDB_2dmp.png) |
Available structures |
---|
PDB | Ortholog search: PDBe RCSB |
---|
List of PDB id codes |
---|
2DMP, 3NAU |
|
|
Identifiers |
---|
Aliases | ZHX2, AFR1, RAF, zinc fingers and homeoboxes 2 |
---|
External IDs | OMIM: 609185; MGI: 2683087; HomoloGene: 8968; GeneCards: ZHX2; OMA:ZHX2 - orthologs |
---|
Gene location (Human) |
---|
![Chromosome 8 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Ideogram_human_chromosome_8.svg/300px-Ideogram_human_chromosome_8.svg.png) | Chr. | Chromosome 8 (human)[1] |
---|
| Band | 8q24.13 | Start | 122,781,655 bp[1] |
---|
End | 122,974,510 bp[1] |
---|
|
Gene location (Mouse) |
---|
![Chromosome 15 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Ideogram_house_mouse_chromosome_15.svg/260px-Ideogram_house_mouse_chromosome_15.svg.png) | Chr. | Chromosome 15 (mouse)[2] |
---|
| Band | 15 D1|15 24.01 cM | Start | 57,558,061 bp[2] |
---|
End | 57,703,228 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - superficial temporal artery
- dorsal motor nucleus of vagus nerve
- saphenous vein
- Skeletal muscle tissue of rectus abdominis
- inferior olivary nucleus
- internal globus pallidus
- Skeletal muscle tissue of biceps brachii
- right ventricle
- caput epididymis
- lactiferous duct
|
| Top expressed in | - knee joint
- triceps brachii muscle
- vastus lateralis muscle
- otolith organ
- temporal muscle
- utricle
- skeletal muscle tissue
- medial head of gastrocnemius muscle
- granulocyte
- sternocleidomastoid muscle
|
| More reference expression data |
|
---|
BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d5/PBB_GE_ZHX2_203556_at_fs.png/250px-PBB_GE_ZHX2_203556_at_fs.png) | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - DNA-binding transcription factor activity
- DNA binding
- protein binding
- protein homodimerization activity
- transcription corepressor activity
- metal ion binding
- identical protein binding
- protein heterodimerization activity
- nucleic acid binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
| Cellular component | - nucleus
- nucleoplasm
- cytosol
- plasma membrane
| Biological process | - regulation of transcription by RNA polymerase II
- negative regulation of transcription, DNA-templated
- regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- mRNA catabolic process
- negative regulation of neuron differentiation
- somatic stem cell population maintenance
- transcription, DNA-templated
- retinal bipolar neuron differentiation
- nervous system development
- cell differentiation
| Sources:Amigo / QuickGO |
|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|