Secretogranin-1

Protein-coding gene in the species Homo sapiens
CHGB
Identifiers
AliasesCHGB, SCG1, chromogranin B
External IDsOMIM: 118920; MGI: 88395; HomoloGene: 1375; GeneCards: CHGB; OMA:CHGB - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for CHGB
Genomic location for CHGB
Band20p12.3Start5,911,510 bp[1]
End5,925,353 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • paraflocculus of cerebellum

  • cerebellar vermis

  • beta cell

  • anterior pituitary

  • pons

  • right hemisphere of cerebellum

  • superior vestibular nucleus

  • endothelial cell

  • middle temporal gyrus

  • prefrontal cortex
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • hormone activity
Cellular component
  • secretory granule
  • extracellular region
  • endoplasmic reticulum lumen
  • extracellular space
Biological process
  • post-translational protein modification
  • regulation of signaling receptor activity
  • signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

1114

12653

Ensembl

ENSG00000089199

ENSMUSG00000027350

UniProt

P05060

P16014

RefSeq (mRNA)

NM_001819

NM_007694

RefSeq (protein)

NP_001810

NP_031720

Location (UCSC)Chr 20: 5.91 – 5.93 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Secretogranin-1, also known as Chromogranin B, is a protein that in humans is encoded by the CHGB gene.[4][5] It is a member of the granin protein family.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000089199 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ UNIPROT: P05060 Retrieved 27 November 2019
  5. ^ HGNC: HGNC:1930 Retrieved 27 November 2019
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