RIOX1

Protein-coding gene in humans
RIOX1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4CCJ, 4CCK, 4CCM, 4CCN, 4CCO, 4DIQ, 4E4H, 4Y4R, 4Y33, 4Y3O

Identifiers
AliasesRIOX1, MAPJD, NO66, ROX, hsNO66, URLC2, C14orf169, chromosome 14 open reading frame 169, ribosomal oxygenase 1, JMJD9
External IDsOMIM: 611919; MGI: 1919202; HomoloGene: 11366; GeneCards: RIOX1; OMA:RIOX1 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for RIOX1
Genomic location for RIOX1
Band14q24.3Start73,490,933 bp[1]
End73,493,394 bp[1]
Gene location (Mouse)
Chromosome 12 (mouse)
Chr.Chromosome 12 (mouse)[2]
Chromosome 12 (mouse)
Genomic location for RIOX1
Genomic location for RIOX1
Band12|12 D1Start83,997,382 bp[2]
End83,999,725 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • oocyte

  • sperm

  • gonad

  • secondary oocyte

  • granulocyte

  • testicle

  • right testis

  • ganglionic eminence

  • mucosa of ileum

  • left testis
Top expressed in
  • granulocyte

  • primitive streak

  • epiblast

  • endocardial cushion

  • abdominal wall

  • hair follicle

  • somite

  • embryo

  • renal corpuscle

  • medullary collecting duct
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • oxidoreductase activity
  • protein binding
  • dioxygenase activity
  • metal ion binding
  • histone H3-methyl-lysine-4 demethylase activity
  • histone H3-methyl-lysine-36 demethylase activity
  • 2-oxoglutarate-dependent dioxygenase activity
  • iron ion binding
Cellular component
  • nucleoplasm
  • nucleus
  • nucleolus
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • histone H3-K4 demethylation
  • histone H3-K36 demethylation
  • chromatin remodeling
  • negative regulation of transcription, DNA-templated
  • negative regulation of osteoblast differentiation
  • peptidyl-arginine hydroxylation
  • chromatin organization
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79697

71952

Ensembl

ENSG00000170468

ENSMUSG00000046791

UniProt

Q9H6W3

Q9JJF3

RefSeq (mRNA)

NM_024644

NM_023633

RefSeq (protein)

NP_078920

NP_076122

Location (UCSC)Chr 14: 73.49 – 73.49 MbChr 12: 84 – 84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ribosomal oxygenase 1 is a protein that in humans is encoded by the RIOX1 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170468 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046791 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Chromosome 14 open reading frame 169". Retrieved 2016-04-09.

Further reading

  • Eilbracht J, Reichenzeller M, Hergt M, Schnölzer M, Heid H, Stöhr M, Franke WW, Schmidt-Zachmann MS (2004). "NO66, a highly conserved dual location protein in the nucleolus and in a special type of synchronously replicating chromatin". Mol. Biol. Cell. 15 (4): 1816–32. doi:10.1091/mbc.E03-08-0623. PMC 379278. PMID 14742713.

External links

  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Ribosomal oxygenase 1 (RIOX1)
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