N-acetylneuraminate epimerase

N-acetylneuraminate epimerase
Identifiers
EC no.5.1.3.24
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N-acetylneuraminate epimerase (EC 5.1.3.24, sialic acid epimerase, N-acetylneuraminate mutarotase, sialic acid mutarotase, YjhT, NanM) is an enzyme with systematic name N-acetyl-alpha-neuraminate 2-epimerase.[1] This enzyme catalyses the following chemical reaction

N-acetyl-alpha-neuraminate {\displaystyle \rightleftharpoons } N-acetyl-beta-neuraminate

Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages.

See also

  • sialic acid
    • N-acetylneuraminate
  • Mutarotation

References

  1. ^ Severi E, Müller A, Potts JR, Leech A, Williamson D, Wilson KS, Thomas GH (February 2008). "Sialic acid mutarotation is catalyzed by the Escherichia coli beta-propeller protein YjhT". The Journal of Biological Chemistry. 283 (8): 4841–9. doi:10.1074/jbc.M707822200. PMID 18063573.

External links

  • N-acetylneuraminate+epimerase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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Isomerases: Epimerase and racemases (EC 5.1)
5.1.1: Amino acids
5.1.2: Hydroxy acids5.1.3: Carbohydrates
5.1.99: Other
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