DUSP27

Protein-coding gene in the species Homo sapiens
STYXL2
Identifiers
AliasesSTYXL2, dual specificity phosphatase 27 (putative), dual specificity phosphatase 27, atypical, serine/threonine/tyrosine interacting like 2, DUSP27
External IDsMGI: 2685055; HomoloGene: 18949; GeneCards: STYXL2; OMA:STYXL2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for STYXL2
Genomic location for STYXL2
Band1q24.1Start167,094,075 bp[1]
End167,129,165 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for STYXL2
Genomic location for STYXL2
Band1|1 H2.3Start165,925,717 bp[2]
End165,955,491 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • myocardium of left ventricle

  • cardiac muscle tissue of right atrium

  • tibialis anterior muscle

  • Skeletal muscle tissue of rectus abdominis

  • deltoid muscle

  • apex of heart

  • right ventricle

  • quadriceps femoris muscle

  • vastus lateralis muscle

  • biceps brachii
Top expressed in
  • interventricular septum

  • knee joint

  • medial head of gastrocnemius muscle

  • soleus muscle

  • muscle of thigh

  • quadriceps femoris muscle

  • skeletal muscle tissue

  • tibialis anterior muscle

  • temporal muscle

  • triceps brachii muscle
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein tyrosine/serine/threonine phosphatase activity
  • phosphatase activity
Cellular component
  • cytoplasm
  • sarcomere
Biological process
  • protein dephosphorylation
  • dephosphorylation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

92235

240892

Ensembl

ENSG00000198842

ENSMUSG00000026564

UniProt

Q5VZP5

Q148W8

RefSeq (mRNA)

NM_001080426

NM_001033344
NM_001160049

RefSeq (protein)

NP_001073895

NP_001028516
NP_001153521

Location (UCSC)Chr 1: 167.09 – 167.13 MbChr 1: 165.93 – 165.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dual specificity phosphatase 27, atypical is a protein that in humans is encoded by the DUSP27 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198842 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026564 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Dual specificity phosphatase 27, atypical". Retrieved 2018-10-20.

Further reading

  • Ehret GB, O'Connor AA, Weder A, Cooper RS, Chakravarti A (December 2009). "Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study". Eur. J. Hum. Genet. 17 (12): 1650–7. doi:10.1038/ejhg.2009.94. PMC 2783544. PMID 19536175.
  • Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.


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