Cefmenoxime
Chemical compound
- J01DD05 (WHO) S01AA31 (WHO), S02AA18 (WHO)
- (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-
2-methoxyimino-acetyl]amino}-3-[(1-methyltetrazol-
5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]
oct-2-ene-2-carboxylic acid
- 65085-01-0 Y
- 9570757
- DB00267 Y
- 7845223 Y
- KBZ4844CXN
- D07641 Y
- CHEBI:55490 Y
- ChEMBL1201224 N
- DTXSID2022755
- Interactive image
- O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)/c3nc(sc3)N)CSc4nnnn4C)C(=O)O
- InChI=1S/C16H17N9O5S3/c1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7/h5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29)/b21-8-/t9-,13-/m1/s1 Y
- Key:HJJDBAOLQAWBMH-YCRCPZNHSA-N Y
Cefmenoxime is a third-generation cephalosporin antibiotic.[citation needed]
References
External links
- Diseases Database (DDB): 30892
- Yokota N, Koguchi M, Suzuki Y, Fukayama S, Ishihara R, Deguchi K, Oda S, Tanaka S, Nakane Y, Fukumoto T (1995). "Antibacterial activities of cefmenoxime against recent fresh clinical isolates from patients in sinusitis". Jpn J Antibiot. 48 (5): 602–9. PMID 7637194.
- Paladino J, Fell R (1994). "Pharmacoeconomic analysis of cefmenoxime dual individualization in the treatment of nosocomial pneumonia". Ann Pharmacother. 28 (3): 384–9. doi:10.1177/106002809402800316. PMID 8193431. S2CID 29444681.
- Duncker G, Reich U, Krausse R (1994). "Cefmenoxime in corneal organ culture". Ophthalmologica. 208 (5): 262–6. doi:10.1159/000310505. PMID 7816419.
- v
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(inhibit synthesis
of peptidoglycan
layer of bacterial
cell wall by binding
to and inhibiting
PBPs, a group of
D-alanyl-D-alanine
transpeptidases)
Glycopeptides Lipoglycopeptides |
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Lipopeptides |
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Polymyxins |
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Other |
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- Inhibit PG subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
- Hydrolyze NAM-NAG
- Tyrothricin
- Isoniazid#
- Teixobactin
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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